Hepatitis B reactivation in patients with multiple myeloma and isolated positive hepatitis B core antibody: a call for greater cognizance.

作者: Ju Dong Yang , Mohit Girotra , Alejandro Restrepo , Sarah Waheed , Bart Barlogie

DOI: 10.1016/S1665-2681(19)30855-5

关键词:

摘要: Hepatitis B virus (HBV) reactivation is a well-established complication of severe immunosuppression in patients with hematologic malignancy and positive hepatitis surface antigen (HBsAg). Patients who receive high-dose chemotherapy, corticosteroids, rituximab, or have bone marrow transplant are particularly at increased risk for HBV reactivation. However, limited information available the literature regarding isolated anti-HBc, setting multiple myeloma (MM). We report two cases MM anti-HBc rather atypical presentation. In conclusion, our highlight that clinicians need to be cognizant about this potentially fatal but preventable chemotherapy immunosuppression.

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