Laser-engineered dissolving microneedle arrays for transdermal macromolecular drug delivery.

作者: Katarzyna Migalska , Desmond I. J. Morrow , Martin J. Garland , Raj Thakur , A. David Woolfson

DOI: 10.1007/S11095-011-0419-4

关键词:

摘要: Purpose To assess the feasibility of transdermal macromolecule delivery using novel laser-engineered dissolving microneedles (MNs) prepared from aqueous blends 20% w/w poly(methylvinylether maleic anhydride) (PMVE/MA) in vitro and vivo.

参考文章(47)
Omathanu Pillai, Ramesh Panchagnula, Transdermal iontophoresis of insulin. V. Effect of terpenes. Journal of Controlled Release. ,vol. 88, pp. 287- 296 ,(2003) , 10.1016/S0168-3659(03)00065-8
Omathanu Pillai, S.D. Borkute, N. Sivaprasad, Ramesh Panchagnula, Transdermal iontophoresis of insulin II. Physicochemical considerations International Journal of Pharmaceutics. ,vol. 254, pp. 271- 280 ,(2003) , 10.1016/S0378-5173(03)00034-6
James A Matriano, Michel Cormier, Juanita Johnson, Wendy A Young, Margaret Buttery, Kofi Nyam, Peter E Daddona, None, Macroflux microprojection array patch technology: a new and efficient approach for intracutaneous immunization. Pharmaceutical Research. ,vol. 19, pp. 63- 70 ,(2002) , 10.1023/A:1013607400040
Jia-You Fang, Woan-Ruoh Lee, Shing-Chuan Shen, Hsin-Yuan Wang, Chia-Lang Fang, Chung-Hong Hu, Transdermal delivery of macromolecules by erbium:YAG laser. Journal of Controlled Release. ,vol. 100, pp. 75- 85 ,(2004) , 10.1016/J.JCONREL.2004.08.009
Lotte Langkjær, Jens Brange, Gerold M Grodsky, Richard H Guy, Iontophoresis of monomeric insulin analogues in vitro: effects of insulin charge and skin pretreatment. Journal of Controlled Release. ,vol. 51, pp. 47- 56 ,(1998) , 10.1016/S0168-3659(97)00155-7
Yukako Ito, Yoshinori Ohashi, Atsushi Saeki, Nobuyuki Sugioka, Kanji Takada, Antihyperglycemic effect of insulin from self-dissolving micropiles in dogs. Chemical & Pharmaceutical Bulletin. ,vol. 56, pp. 243- 246 ,(2008) , 10.1248/CPB.56.243
Shilpa Kaushik, Allen H. Hord, Donald D. Denson, Devin V. McAllister, Sudhasinee Smitra, Mark G. Allen, Mark R. Prausnitz, Lack of pain associated with microfabricated microneedles. Anesthesia & Analgesia. ,vol. 92, pp. 502- 504 ,(2001) , 10.1097/00000539-200102000-00041
Ryan F. Donnelly, Rita Majithiya, Thakur Raghu Raj Singh, Desmond I. J. Morrow, Martin J. Garland, Yusuf K. Demir, Katarzyna Migalska, Elizabeth Ryan, David Gillen, Christopher J. Scott, A. David Woolfson, Design, Optimization and Characterisation of Polymeric Microneedle Arrays Prepared by a Novel Laser-Based Micromoulding Technique Pharmaceutical Research. ,vol. 28, pp. 41- 57 ,(2011) , 10.1007/S11095-010-0169-8
Yukako Ito, Atsushi Saeki, Keiji Shiroyama, Nobuyuki Sugioka, Kanji Takada, Percutaneous absorption of interferon-α by self-dissolving micropiles Journal of Drug Targeting. ,vol. 16, pp. 243- 249 ,(2008) , 10.1080/10611860801902575