Nonfunctional Pancreatic Neuroendocrine Tumors

摘要: Pancreatic neuroendocrine tumors are a group of rare, heterogeneous neoplasms that have been increasing in incidence the past few decades largely because diagnosis pancreatic incidentalomas on cross-sectional imaging. Although these classically associated with clinical syndromes result from excess secretion particular hormones, most nonfunctional presenting symptoms secondary to mass effect, metastatic disease, or as incidental findings. This article reviews diagnostic algorithm, surgical management, and available systemic therapies for tumors.