Alcohol, Neurodegenerative Disorders, and Calcium Channel Antagonist Receptors

作者: D. A. Greenberg , R. O. Messing , S. S. Marks , C. L. Carpenter , D. L. Watson

DOI: 10.1007/978-3-642-73914-9_43

关键词:

摘要: Our current understanding of the physiology and pharmacology voltage-dependent Ca2+ channels owes considerable debt to use -channel antagonist drugs as probes channel structure function. The availability these pivotal role in normal cellular activity have led workers diverse fields, including neurology, psychiatry, cardiology, endocrinology, search for changes function or number that may be important pathophysiology clinical diseases. This has gained impetus from studies genetically determined diseases animals, such congenital cardiomyopathy hamsters (Wagner et al. 1986) muscular dysgenesis mice (Pincon-Raymond 1985), which expression receptors been detected.

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