Chromosomal Translocations in Yeast Induced by Low Levels of DNA Polymerase: A Model for Chromosome Fragile Sites

作者: Francene J. Lemoine , Natasha P. Degtyareva , Kirill Lobachev , Thomas D. Petes

DOI: 10.1016/J.CELL.2004.12.039

关键词:

摘要: In the yeast Saccharomyces cerevisiae, reduced levels of the replicative α DNA polymerase result in greatly elevated frequencies of chromosome translocations and chromosome loss. …

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