Animal models of oxidative stress, aging, and therapeutic antioxidant interventions
作者： Simon Melov
DOI: 10.1016/S1357-2725(02)00086-9
关键词:
摘要: Oxidative stress is a ubiquitous phenomena in all cell types, and it primarily produced mitochondria which are essential for multicellular life. targets can be wide ranging include nucleic acids variety of macromolecules. This review discusses the role oxidative context animal models, focusing particular on models aging, as well development new class therapeutic small molecular weight antioxidants that have proven effective extending lifespan simple invertebrate nematode.
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