Toll-like receptor 1 polymorphisms affect innate immune responses and outcomes in sepsis
作者： Mark M. Wurfel , Anthony C. Gordon , Tarah D. Holden , Frank Radella , Jeanna Strout
DOI: 10.1164/RCCM.200803-462OC
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摘要: Rationale: Polymorphisms affecting Toll-like receptor (TLR)–mediated responses could predispose to excessive inflammation during an infection and contribute to an increased risk for …
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Philipp Henneke, Shaynoor Dramsi, Giuseppe Mancuso, Kamila Chraibi, Elisabeth Pellegrini, Christian Theilacker, Johannes Hübner, Sandra Santos-Sierra, Giuseppe Teti, Douglas T. Golenbock, Claire Poyart, Patrick Trieu-Cuot, Lipoproteins Are Critical TLR2 Activating Toxins in Group B Streptococcal Sepsis Journal of Immunology. ,vol. 180, pp. 6149- 6158 ,(2008) , 10.4049/JIMMUNOL.180.9.6149
Nancy C. Arbour, Eva Lorenz, Brian C. Schutte, Joseph Zabner, Joel N. Kline, Michael Jones, Kathy Frees, Janet L. Watt, David A. Schwartz, TLR4 mutations are associated with endotoxin hyporesponsiveness in humans. Nature Genetics. ,vol. 25, pp. 187- 191 ,(2000) , 10.1038/76048
Lon R Cardon, John I Bell, None, Association study designs for complex diseases Nature Reviews Genetics. ,vol. 2, pp. 91- 99 ,(2001) , 10.1038/35052543
Shizuo Akira, Kiyoshi Takeda, Tsuneyasu Kaisho, Toll-like receptors: critical proteins linking innate and acquired immunity Nature Immunology. ,vol. 2, pp. 675- 680 ,(2001) , 10.1038/90609
Mark M. Wurfel, William Y. Park, Frank Radella, John Ruzinski, Andrew Sandstrom, Jeanna Strout, Roger E. Bumgarner, Thomas R. Martin, Identification of high and low responders to lipopolysaccharide in normal subjects: an unbiased approach to identify modulators of innate immunity Journal of Immunology. ,vol. 175, pp. 2570- 2578 ,(2005) , 10.4049/JIMMUNOL.175.4.2570
Adeline M. Hajjar, D. Shane O’Mahony, Adrian Ozinsky, David M. Underhill, Alan Aderem, Seymour J. Klebanoff, Christopher B. Wilson, Cutting Edge: Functional Interactions Between Toll-Like Receptor (TLR) 2 and TLR1 or TLR6 in Response to Phenol-Soluble Modulin Journal of Immunology. ,vol. 166, pp. 15- 19 ,(2001) , 10.4049/JIMMUNOL.166.1.15
J. D. Storey, R. Tibshirani, Statistical significance for genomewide studies Proceedings of the National Academy of Sciences of the United States of America. ,vol. 100, pp. 9440- 9445 ,(2003) , 10.1073/PNAS.1530509100
Sameena S. Khan, Meghan S. Smith, Debra Reda, Anthony F. Suffredini, J. Philip McCoy, Multiplex bead array assays for detection of soluble cytokines: Comparisons of sensitivity and quantitative values among kits from multiple manufacturers Cytometry Part B-clinical Cytometry. ,vol. 61, pp. 35- 39 ,(2004) , 10.1002/CYTO.B.20021
E SCHIPPERS, C VANTVEER, S VANVOORDEN, C MARTINA, T HUIZINGA, S LECESSIE, J VANDISSEL, IL-10 and toll-like receptor-4 polymorphisms and the in vivo and ex vivo response to endotoxin Cytokine. ,vol. 29, pp. 215- 228 ,(2005) , 10.1016/J.CYTO.2004.12.005
Richard S. Hotchkiss, Irene E. Karl, The pathophysiology and treatment of sepsis. The New England Journal of Medicine. ,vol. 348, pp. 138- 150 ,(2003) , 10.1056/NEJMRA021333