Signet ring-like light chain myeloma with systemic spread.

摘要: The morphological presentation of malignant plasma cells in multiple myeloma (MM) varies from mature to anaplastic with only one reported case signet ring variant. We describe here another ring-like lambda light chain MM associated extra-skeletal spread lymph nodes, spleen and liver. clinical pathological presentations were atypical no evidence bone-lytic lesions or monoclonal component on protein electrophoresis, leading a delay several years the diagnosis. Recognition this entity may help an early diagnosis rare