Standardization of transfusion practice in organ donors using the Digital Intern, an electronic decision support algorithm.

摘要: Background Prospective clinical trials support restrictive thresholds for red blood cell (RBC) transfusion. Nonsurvivable donors are a major source of organs transplantation. The Digital Intern (DI) is computer algorithm to standardize donor care that includes more transfusion threshold. impact standardized and RBC in organ donors, as determined by the DI, has not been reported. Study design methods We conducted retrospective cohort study compare practice DI (n = 100) historic group physician-managed 90). Transfusion rates, number units transfused, pretransfusion laboratory values were compared between groups. variability these parameters was also Finally, transplanted per each compared. Results mean time 25.9 ± 15.2 hours different In 19% transfused 26% control (p 0.3). less (1 unit vs. 2 transfusion, p 0.03) hematocrit lower (23% 27%, 0.01). latter two significantly group. similar both groups (3.24 [DI] 3.03 [control], 0.37). Conclusion provides standardization reduces use without compromising transplantable organs.