Nuclear accumulation of p53 protein is mediated by several nuclear localization signals and plays a role in tumorigenesis.
作者： G Shaulsky , N Goldfinger , A Ben-Ze'ev , V Rotter
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摘要: … nuclear compartment. The C terminus of the p53 molecule contains a cluster of several nuclear localization signals … NLS sequences found in other nuclear proteins. The other two NLSs, …
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