Genome-wide studies in multiple myeloma identify XPO1/CRM1 as a critical target validated using the selective nuclear export inhibitor KPT-276.
作者： J Schmidt , E Braggio , K M Kortuem , J B Egan , Y X Zhu
DOI: 10.1038/LEU.2013.172
关键词:
摘要: … We have previously published that XPO1/CRM1 was identified as one of the 55 most vulnerable targeting in MM, using high-throughput RNAi screening on 7622 druggable genes. …
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