Common Data Elements for Traumatic Brain Injury: Recommendations From the Biospecimens and Biomarkers Working Group

摘要: Recent advances in genomics, proteomics, and biotechnology have provided unprecedented opportunities for translational research personalized medicine. Human biospecimens biofluids represent an important resource from which molecular data can be generated to detect classify injury identify mechanisms therapeutic targets. To date, there has been considerable variability biospecimen biofluid collection, storage, processing traumatic brain (TBI) studies. realize the full potential of this resource, standardization adoption best practice guidelines are required insure quality consistency these specimens. The aim Biospecimens Biomarkers Working Group was provide recommendations core elements TBI develop standardize accessibility Consensus were developed through interactions with focus groups input stakeholders participating interagency workshop on Standardization Data Collection Psychological Health held Washington, DC, March 2009. With standards practices, future investigators will able obtain across multiple studies reduced costs effort accelerate progress genomic, proteomic, metabolomic TBI.