作者: Benjamin Solomon , Peter Savas , Brett Hughes
DOI: 10.3978/J.ISSN.2072-1439.2013.08.52
关键词:
摘要: Advances in the treatment of non-small cell lung cancer (NSCLC) over last decade have predominantly involved development therapies directed at molecular targets such as mutations epidermal growth factor receptor (EGFR) or rearrangements anaplastic lymphoma kinase (ALK) gene. Other been discovered low frequency, with multiple agents approved for these rare subtypes. The tumour microenvironment has also provided opportunities targeting angiogenesis and host immune response. This review will provide an overview current targeted NSCLC promising approaches on horizon.