Abnormal cerebellum density in victims of rape with post-traumatic stress disorder: Voxel-based analysis of magnetic resonance imaging investigation
作者： Shuang-Ge Sui , Yan Zhang , Ming-Xiang Wu , Jian-Min Xu , Lian Duan
DOI: 10.1111/J.1758-5872.2010.00076.X
关键词:
摘要: Introduction: Based on early studies of non-motor function in the cerebellum and dysfunction post-traumatic stress disorder ( PTSD) patients, we presumed that was involved neuropathology cognitive emotional processing PTSD while density some sub-areas patients most likely abnormal. Methods: Eleven female victims rape with 12 age-matched normal controls received 1.5 T 3D magnetic resonance imaging (MRI) scan. The scans were then analyzed using voxel-based morphometry 2 VBM2) toolbox. Results: Victims showed increased left side compared (P<0.001), especially pyramis x = -9, y -72, z -36; k 519; t 4.70), uvula -4, -66, -35; 256; 4.02), declive -6, -69, -30; 213; 3.84) nodule -63, -31; 147; 3.93). In addition, controls, group significant differences gray matter other brain areas, including frontal lobe, parietal occipital lobe insula, posterior cingulate, amygdala hippocampus (P<0.005). Discussion: These finding suggest may be functional compensation neurocircuitry PTSD.
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