β-p-Hydroxyphenylhydracrylic acid as a urinary constituent in a patient with gastrointestinal disease

作者: S.K. Wadman , C. van der Heiden , D. Ketting , J.P. Kamerling , J.F.G. Vliegenthart

DOI: 10.1016/0009-8981(73)90328-8

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摘要: Abstract In this paper the isolation of β - p -liydroxyphenylhydracrylic acid from urine a patient with severely impaired intestinal amino resorption is described. The compound has been identified by mass spectrometry. Mass spectrometry and gas chromatography parameters are given. behaviour on twodimensional thin-layer (or paper) chromatograms illustrated. -hydroxyphenylhydracrylic aciduria must be very rare, even in patients resorption. Probably it reflects high influx -coumaric -hydroxyphenylpropionic acids (both bacterial metabolites non-absorbed tyrosine) under exceptional conditions heavily loaded β-oxidation MCT administration.

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