Studies on drug metabolism by use of isotopes XXVI: Determination of urinary metabolites of rutin in humans
作者： Takashi Furuta , Masanobu Horie , Shigeo Baba , Hisashi Nakagawa
关键词: Biochemistry 、 Urine 、 Rutin 、 Mass spectrometry 、 Urinary system 、 Chemistry 、 Isotope 、 Drug metabolism 、 Quercetin 、 Chromatography
摘要: Abstract Determination of urinary metabolites orally administered rutin and rutin-2′, 5′, 6′- d 3 in humans was carried out by TLC GLC-mass spectrometry. In human urine, 3-hydroxyphenylacetic acid, 3-methoxy-4-hydroxyphenylacetic 3, 4-dihydroxyphenylacetic 4-dihydroxytoluene, β- m -hydroxyphenylhydracrylic acid were identified as metabolites. Unchanged quercetin not present the urine.
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