Active and passive smoking – New insights on the molecular composition of different cigarette smoke aerosols by LDI–FTICRMS

作者: Sébastien Schramm , Vincent Carré , Jean-Luc Scheffler , Frédéric Aubriet

DOI: 10.1016/J.ATMOSENV.2014.04.052

关键词:

摘要: Abstract The aerosol generated when a cigarette is smoked significant indoor contaminant. Both smokers and non-smokers can be exposed to this class of pollutants. Nevertheless, they are not the same kind smoke. active smoker breathes in mainstream smoke (MSS) during puff, whereas passive inhales only by lit between two puffs (SSS) but also exhaled (EXS). fraction EXS has until now been poorly documented; its composition expected different from MSS. This study aims investigate complex better understand difference exposure smokers. To address this, in-situ laser desorption ionisation Fourier transform ion cyclotron mass spectrometry (LDI–FTICRMS) was used characterise Results clearly indicated many similarities samples differences with MSS SSS aerosol. comparison allowed chemicals retained smoker's lungs identified, convolution compositions were considered relevant exposition smoker. As consequence, thought mainly polar unsaturated oxygenated nitrogenated organics, compared highly compounds

参考文章(62)
Alan Rodgman, Thomas Albert Perfetti, The Chemical Components of Tobacco and Tobacco Smoke ,(2008)
Hitoshi Asakura, Smoking Tobacco and Gastrointestinal Pathophysiology and Diseases Wiley‐VCH Verlag GmbH & Co. KGaA. pp. 239- 256 ,(2011) , 10.1002/9783527635320.CH12
Barbara Messner, David Bernhard, Smoking and cardiovascular disease: mechanisms of endothelial dysfunction and early atherogenesis. Arteriosclerosis, Thrombosis, and Vascular Biology. ,vol. 34, pp. 509- 515 ,(2014) , 10.1161/ATVBAHA.113.300156
Eman Allam, Weiping Zhang, Cunge Zheng, Richard L. Gregory, L. Jack Windsor, Smoking and Oral Health John Wiley & Sons, Ltd. pp. 257- 280 ,(2011) , 10.1002/9783527635320.CH13
Thomas E. Sussan, Shyam Biswal, Smoking and COPD and Other Respiratory Diseases Wiley‐VCH Verlag GmbH & Co. KGaA. pp. 167- 190 ,(2011) , 10.1002/9783527635320.CH9
Frédéric Aubriet, Vincent Carré, Potential of laser mass spectrometry for the analysis of environmental dust particles--a review Analytica Chimica Acta. ,vol. 659, pp. 34- 54 ,(2010) , 10.1016/J.ACA.2009.11.047
Vincent Carré, Lionel Vernex-Loset, Gabriel Krier, Pascal Manuelli, Jean-François Muller, Laser Desorption/Ionization Mass Spectrometry of Diesel Particulate Matter with Charge-Transfer Complexes Analytical Chemistry. ,vol. 76, pp. 3979- 3987 ,(2004) , 10.1021/AC049875C