Theoretical microbubble dynamics in a viscoelastic medium at capillary breaching thresholds

摘要: In order to predict bioeffects in contrast-enhanced diagnostic and therapeutic ultrasound procedures, the dynamics of cavitation microbubbles viscoelastic media must be determined. For this theoretical study, measured 1.5 7.5 MHz pulse pressure waveforms, which were used experimental determinations capillary breaching thresholds for a rat kidney, calculate nucleated from contrast agent microbubbles. A numerical model tissue was developed based on Keller-Miksis equation (a compressible extension Rayleigh-Plesset spherical bubble dynamics), with Kelvin-Voigt constitutive relation. From model, corresponding experimentally obtained Values maximum radius temperature previously determined bioeffect computed range pulses sizes comparis...