Anthocyanin-rich extract from Hibiscus sabdariffa calyx counteracts UVC-caused impairments in rats

作者: Hatice Uce Ozkol , Ismail Koyuncu , Yasin Tuluce , Nihat Dilsiz , Sinan Soral

DOI: 10.3109/13880209.2014.980586

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摘要: AbstractContext: Ultraviolet radiation (UV) was reported to cause oxidative stress. Hibiscus sabdariffa L. (Malvaceae) calyx is commonly used in traditional Asian and African medicines possesses strong antioxidant capacity due its anthocyanin (ANTH) content.Objective: This study researched the possible protective role of extract (HSCE) UVC exposure rats.Material methods: Levels serum enzymes, renal function tests, some oxidant/antioxidant biomarkers skin, lens, retina tissues were monitored. Rats exposed 4 h daily for 40 d simultaneously received HSCE containing 2.5, 5, 10 mg doses ANTH drinking water.Results: Significant (p < 0.05) increases levels aminotransferases, lactate dehydrogenase, urea, creatinine, uric acid noted after exposure. In tissues, total oxidant status, stress index, lipid peroxidation, protein oxidation escalated markedly where...

参考文章(51)
Hélène Paul, "Hibiscus sabdariffa" L Paris 5. ,(1995)
Mervat Ahmed Ali, Eman Mohamed Aly, Effects of bilberry on deoxyribonucleic Acid damage and oxidant-antioxidant balance in the lens, induced by ultraviolet radiation. The Malaysian journal of medical sciences. ,vol. 21, pp. 11- 18 ,(2014)
Ganiyu Oboh, Oluwaseun J. Agbebi, Ayodele J. Akinyemi, Adedayo O. Ademiluyi, Anthocyanin - Rich Red Dye of Hibiscus Sabdariffa Calyx Modulates Cisplatin-induced Nephrotoxicity and Oxidative Stress in Rats. International journal of biomedical science : IJBS. ,vol. 9, pp. 243- 248 ,(2013)
Rodney L. Levine, Donita Garland, Cynthia N. Oliver, Adolfo Amici, Isabel Climent, Anke-G. Lenz, Bong-Whan Ahn, Shmuel Shaltiel, Earl R. Stadtman, Determination of carbonyl content in oxidatively modified proteins. Methods in Enzymology. ,vol. 186, pp. 464- 478 ,(1990) , 10.1016/0076-6879(90)86141-H
A. Lewis Farr, Oliver H. Lowry, Rose J. Randall, Nira J. Rosebrough, Protein Measurement with the Folin Phenol Reagent Journal of Biological Chemistry. ,vol. 193, pp. 265- 275 ,(1951)
ALAN Y. W. LEE, STEPHEN S. M. CHUNG, Contributions of polyol pathway to oxidative stress in diabetic cataract The FASEB Journal. ,vol. 13, pp. 23- 30 ,(1999) , 10.1096/FASEBJ.13.1.23
Richard O. Recknagel, Eric A. Glende, James A. Dolak, Robert L. Waller, Mechanisms of carbon tetrachloride toxicity Pharmacology & Therapeutics. ,vol. 43, pp. 139- 154 ,(1989) , 10.1016/0163-7258(89)90050-8
Douglas Darr, Irwin Fridovich, Free radicals in cutaneous biology. Journal of Investigative Dermatology. ,vol. 102, pp. 671- 675 ,(1994) , 10.1111/1523-1747.EP12374036
Octavio Carvajal-Zarrabal, Dulce María Barradas-Dermitz, Zaida Orta-Flores, Patricia Margaret Hayward-Jones, Cirilo Nolasco-Hipólito, M Guadalupe Aguilar-Uscanga, Anilú Miranda-Medina, Kopli Bin Bujang, Hibiscus sabdariffa L., roselle calyx, from ethnobotany to pharmacology. Journal of Experimental Pharmacology. ,vol. 4, pp. 25- 39 ,(2012) , 10.2147/JEP.S27974