The p53 functional circuit.

作者: Arnold J. Levine , Shengkan Jin

DOI: 10.1242/JCS.114.23.4139

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摘要: The p53 gene is a tumor suppressor that plays critical role in safeguarding the integrity of genome. mutated or part its regulatory circuit functionally inactivated almost all cancers, which highlights importance preventing tumorigenesis. protein

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