Stable pharmaceutical composition of a water-soluble vinorelbine salt
作者： Bruno Paillard , Joël Bougaret , Jean-Louis Avan
DOI:
关键词:
摘要: A stable pharmaceutical composition comprising a water-soluble vinorelbine salt and at least one diluent lubricant, characterized in that it appears solid form intended for oral administration. The water soluble is advantageously ditartrate. as gelatin capsule or tablet.
lens.org 参考文章(16)
Elie Leverd, Joel Bougaret, Marie Dominique Ibarra, Stable solid dispersion of a derivative of vinca alkaloid and process for manufacturing it ,(2005)
Elie Leverd, Norbert Heintz, Marie-Madeleine Bohn, Joel Bougaret, Oral pharmaceutical composition for soft capsules containing vinorelbine and method of treatment ,(2003)
Linda Margarite Thurmond, Julie Beth Stimmel, Vincent Clark Knick, Pharmaceutical comprising an agent that blocks the cell cycle and an antibody ,(2001)
Gerard Leduc, Pascal Oury, Pascal Suplie, Patrice Debregeas, Microgranules containing cisplatin ,(1998)
Elie Leverd, Marie-Dominique Ibarra, Joel Bougaret, Pharmaceutical composition of vinflunine which is intended for parenteral administration preparation method thereof and use of same ,(2004)
Anna Kruczynski, Fabien Zunino, Robert Kiss, Jean-Claude Jacquesy, Marie-Paule Jouannetaud, Dennis Bigg, Jacques Fahy, Christian Berrier, Antimitotic binary alkaloid derivatives from catharanthus roseus ,(1994)
E K Rowinsky, D A Noe, D L Trump, E P Winer, V S Lucas, W A Wargin, J A Hohneker, B Lubejko, S E Sartorius, D S Ettinger, Pharmacokinetic, bioavailability, and feasibility study of oral vinorelbine in patients with solid tumors. Journal of Clinical Oncology. ,vol. 12, pp. 1754- 1763 ,(1994) , 10.1200/JCO.1994.12.9.1754
Richard M. Lush, Jeannine S. McCune, Leticia Tetteh, John A. Thompson, J. J. Mahany, Linda Garland, A. Benjamin. Suttle, Daniel M. Sullivan, The absolute bioavailability of oral vinorelbine in patients with solid tumors. Cancer Chemotherapy and Pharmacology. ,vol. 56, pp. 578- 584 ,(2005) , 10.1007/S00280-005-1025-0
Valerie J. Poirier, David M. Vail, William M. Adams, Kristine E. Burgess, Toxicity, dosage, and efficacy of vinorelbine (Navelbine) in dogs with spontaneous neoplasia. Journal of Veterinary Internal Medicine. ,vol. 18, pp. 536- 539 ,(2004) , 10.1892/0891-6640(2004)18<536:TDAEOV>2.0.CO;2
James J. Kasica, Paolo C. Trubiano, Compressible starches as binders for tablets or capsules ,(1985)