作者: Nikola Škreb , Božica Levak-Švajger , Anton Švajger
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摘要: Experimental results obtained many years ago revealed that during gastrulation (with the primitive streak and mesoderm formation as distinct features) early rodent embryo undergoes essential changes in its response to extrinsic teratogens (Russell & Russell, 1954; Wilson, Skreb, 1961; Skreb Bijelic, 1962; Frank, 1963). It has also been shown ultrastructural, histochemical biosynthetic features of are subject substantial this period (Solter, Damjanov 1970, 1973; Dziadek Adamson, 1978; Bode Dziadek, 1979; Wartiovaara, Leivo Vaheri, Jackson et al. 1981; Franke 1982 a, b ). This suggests a restriction developmental capacities (i.e. loss capacity regulation) groups embryonic cells at stage. According current concept, initial cell population from which starts, resides within ectoderm pregastrulation or preprimitive (primitive primary ectoderm).