作者: Jyrki T. Mäkelä
DOI: 10.1001/ARCHSURG.1995.01430100040009
关键词:
摘要: Objective: To determine whether an intensified follow-up of patients with colorectal cancer can lead to improved reresectability and a better long-term survival. Design: A prospective randomized trial 106 patients. Setting: Oulu University Hospital, referral center in northern Finland. Patients: total consecutive who underwent radical resection for cancer, 54 whom were into conventional group 52 group. Main Outcome Measures: After 5-year follow-up, the time detection recurrence, recurrence rates, first method showing mode reresectability, survival compared between groups. Results: The recurrences identified earlier than (mean±SD, 10±5 months vs 15±10 months). overall rate was 41%, 39% 42% Carcinoembryonic antigen determination most common both Endoscopy ultrasound beneficial group, but computed tomography failed improve diagnostics. did not differ Radical reresections performed on 19% (8/43) patients, 14% (3/21) 22% (5/22) cumulative 54% 59% Conclusion: Earlier recurrent by does either significantly increased or (Arch Surg. 1995;130:1062-1067)