Improving access to novel agents for childhood leukemia.
作者： Weili Sun , Paul S. Gaynon , Richard Sposto , Alan S. Wayne
DOI: 10.1002/CNCR.29267
关键词:
摘要: Leukemia is the most common pediatric cancer. Despite great progress in development of curative therapy, leukemia remains a leading cause death from disease childhood, and survivors are at life-long risk complications treatment. New agents needed to further increase cure rates decrease treatment-associated toxicities. The complex biology aggressive nature childhood leukemia, coupled with relatively small patient population available for study, pose specific challenges new therapies. In this review, authors discuss strategies initiatives designed improve access treatment leukemia.
sci-hub.se 参考文章(83)
Peter J Houghton, Christopher L Morton, Chandra Tucker, Debbie Payne, Edward Favours, Claire Cole, Richard Gorlick, E Anders Kolb, Wendong Zhang, Richard Lock, Hernan Carol, Mimi Tajbakhsh, C Patrick Reynolds, John M Maris, Joshua Courtright, Stephen T Keir, Henry S Friedman, Charles Stopford, Joseph Zeidner, Jianrong Wu, Tiebin Liu, Catherine A Billups, Javed Khan, Sherry Ansher, Jian Zhang, Malcolm A Smith, None, The pediatric preclinical testing program: description of models and early testing results. Pediatric Blood & Cancer. ,vol. 49, pp. 928- 940 ,(2007) , 10.1002/PBC.21078
Todd M. Cooper, Janet Franklin, Robert B. Gerbing, Todd A. Alonzo, Craig Hurwitz, Susana C. Raimondi, Betsy Hirsch, Franklin O. Smith, Prasad Mathew, Robert J. Arceci, James Feusner, Robert Iannone, Robert S. Lavey, Soheil Meshinchi, Alan Gamis, AAML03P1, a pilot study of the safety of gemtuzumab ozogamicin in combination with chemotherapy for newly diagnosed childhood acute myeloid leukemia: a report from the Children's Oncology Group. Cancer. ,vol. 118, pp. 761- 769 ,(2012) , 10.1002/CNCR.26190
Michael J. Burke, Jatinder K. Lamba, Stanley Pounds, Xueyuan Cao, Yogita Ghodke-Puranik, Bruce R. Lindgren, Brenda J. Weigel, Michael R. Verneris, Jeffrey S. Miller, A therapeutic trial of decitabine and vorinostat in combination with chemotherapy for relapsed/refractory acute lymphoblastic leukemia American Journal of Hematology. ,vol. 89, pp. 889- 895 ,(2014) , 10.1002/AJH.23778
Michael J. Rieder, Bruce Carleton, Pharmacogenomics and adverse drug reactions in children Frontiers in Genetics. ,vol. 5, pp. 78- 78 ,(2014) , 10.3389/FGENE.2014.00078
P S Gaynon, , A L Angiolillo, W L Carroll, J B Nachman, M E Trigg, H N Sather, S P Hunger, M Devidas, Long Term Results of the Children’s Cancer Group Studies for Childhood Acute Lymphoblastic Leukemia 1983–2002: a Children’s Oncology Group Report Leukemia. ,vol. 24, pp. 285- 297 ,(2010) , 10.1038/LEU.2009.262
Richard Sposto, Susan Groshen, A wide-spectrum paired comparison of the properties of the Rolling 6 and 3+3 Phase I study designs. Contemporary Clinical Trials. ,vol. 32, pp. 694- 703 ,(2011) , 10.1016/J.CCT.2011.04.009
Ajay Vora, Management of osteonecrosis in children and young adults with acute lymphoblastic leukaemia. British Journal of Haematology. ,vol. 155, pp. 549- 560 ,(2011) , 10.1111/J.1365-2141.2011.08871.X
Huining Kang, I.-Ming Chen, Carla S. Wilson, Edward J. Bedrick, Richard C. Harvey, Susan R. Atlas, Meenakshi Devidas, Charles G. Mullighan, Xuefei Wang, Maurice Murphy, Kerem Ar, Walker Wharton, Michael J. Borowitz, W. Paul Bowman, Deepa Bhojwani, William L. Carroll, Bruce M. Camitta, Gregory H. Reaman, Malcolm A. Smith, James R. Downing, Stephen P. Hunger, Cheryl L. Willman, Gene expression classifiers for relapse free survival and minimal residual disease improve risk classification and out come prediction in pedeatric b-precursor acute lymphoblastic leukemia Blood. ,vol. 115, pp. 1394- 1405 ,(2009) , 10.1182/BLOOD-2009-05-218560
Shafqat Shah, Steven Weitman, Anne-Marie Langevin, Mark Bernstein, Wayne Furman, Charles Pratt, Phase I therapy trials in children with cancer. Journal of Pediatric Hematology Oncology. ,vol. 20, pp. 431- 438 ,(1998) , 10.1097/00043426-199809000-00005
E. Connor, P. Cure, “Creating Hope” and Other Incentives for Drug Development for Children Science Translational Medicine. ,vol. 3, ,(2011) , 10.1126/SCITRANSLMED.3001707