Anti-tumor effects of metformin in animal models of hepatocellular carcinoma: a systematic review and meta-analysis.
作者： Juan Li , Pratika Y. Hernanda , Wichor M. Bramer , Maikel P. Peppelenbosch , Judith van Luijk
DOI: 10.1371/JOURNAL.PONE.0127967
关键词:
摘要: Background Several studies have reported that metformin can reduce the risk of hepatocellular carcinoma (HCC) in diabetes patients. However, direct anti-HCC effects hardly been studied patients, but extensively investigated animal models HCC. We therefore performed a systematic review and meta-analysis evaluating on
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