作者: Maureen McMahon , Kenneth Kalunian
DOI: 10.1016/B978-012455900-4/50279-8
关键词:
摘要: A diagnosis of systemic lupus erythematosus (SLE) is likely if four eleven “the American College Rheumatology criteria for SLE” are met, which given in a table this chapter. The detection autoantibodies patients not only useful establishing SLE, but may also reflect disease activity, correlate with organ involvement, and predict relapse. It important to recognize, however, that no one test or panel can perform all these activities, as increases the specificity usually correspond decreases sensitivity. Additionally, clinical features SLE mediated by antibodies. most common screening immunofluorescence on rodent liver human epithelial (Hep-2) tissue, although enzyme-linked immunosorbent assays (ELISA) available. In selected populations antinuclear antibodies (ANAs) highly sensitive when Hep-2 cells used, over 98 per cent who fulfill have positive test. .