Investigation of polymer hydrogels with memory effect for cefazolin immobilization by small-angle neutron scattering

作者: Yu. V. Kul’velis , V. T. Lebedev , V. A. Trunov , S. S. Ivanchev , O. N. Primanchenko

DOI: 10.1134/S1027451012100102

关键词:

摘要: The method of small-angle neutron scattering has been used for the investigation hydrogels synthesized on basis a cross-linked copolymer 2-hydroxyethyl methacrylate and functional monomers (acrylic acid or dimethylaminoethyl methacrylate) which possess memory effect with respect to target pharmaceutical substance — cefazolin. difference in structure anionic, cationic amphiphilic shown as well relation between ability hydrogel water sorption presence absence Certain structural features confirmed conditions appearance liberation

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