SNAPPE-II application in newborns with very low birth weight: evaluation of adverse outcomes in severe placental dysfunction.

摘要: Aim: The aim of this study was to evaluate the ability admission Score for Neonatal Acute Physiology - Perinatal Extension-II (SNAPPE-II) predict adverse outcome among premature very low birth weight (BW) infants with abnormal Doppler blood flow in uterus secondary severe placental insufficiency early onset. Methods: A total 86 neonates, weighing between 360 and 1498 g, were studied. Descriptive statistics population reported. areas under receiver operating characteristics curves SNAPPE-II calculated. calibration model assessed using technique Hosmer-Lemeshow. Adverse defined as mortality or development following diagnoses: (1) periventricular-intraventricular hemorrhage (PIH); (2) retinopathy prematurity stage 3 4; (3) periventricular leukomalacia ; (4) bronchopulmonary dysplasia; (5) necrotizing enterocolitis (NEC). Results: area curve 0.86 (95% CI: 0.78-0.94) 0.76 0.65-0.86) prediction outcomes. Analyzing each morbidity variable, AUC varied 0.51 NEC 0.72 PIH. Conclusion: shows accuracy highly selective group BW compromised by insufficiency.