Inclusion complex of neohesperidin dihydrochalcone and glucosyl-β-cyclodextrin: Synthesis, characterization, and bitter masking properties in aqueous solutions

摘要: Abstract The objective of this study was to synthesize a new water-soluble bitterness inhibitor—neohesperidin dihydrochalcone (NHDC)/glucosyl- β -cyclodextrin (G- -CD) inclusion complex via ultrasonic-assisted technique in the ethanol aqueous solution, and also assess its bitterness-masking effect on corn peptides (CPs) using descriptive sensory analysis. Under optimal synthetic condition, NHDC payload 278 mg/g rate 74.6%. scanning electron microscopy (SEM) observation demonstrated that inserted into cavity G- -CD. disposition NHDC/G- -CD complexes were affirmed by differential calorimetry (DSC) X-ray diffraction (XRD). Furthermore, molecular structures explored Fourier transform infrared (FT-IR) proton nuclear magnetic resonance ( 1 H NMR). Results clearly indicated formation multicomponent held together hydrophobic interaction or hydrogen bond. CP-debittering assessment showed prepared possessed more superior CP compared single -CD, other inhibitors, such as phosphatidic acid, protein-phosphatidic acid complexes, tannin, neodiosmin. Therefore, has potential use for debittering CP-based food drugs.