Pre-radiotherapy pain intensity and health-related quality of life in patients with bone metastases at various vertebral levels.

摘要: Abstract Purpose The spine is the most common site of bone metastasis from cancer and can be divided into 5 locational subsections, varying in mobility. purpose this research was to determine if mobility metastases-bearing vertebral segment influenced pre-treatment pain intensity or health-related quality life (HR-QoL) for patients about receive palliative radiation therapy painful metastasis. Methods This study a retrospective chart review referred Palliative Radiation Oncology Program, between January 2014 June 2016. main variables included patient-reported Edmonton Symptom Assessment Score intensity, EQ-5D score HR-QoL location (categorized using SINS (mobile, junctional, semi-rigid, rigid)). Various patient, disease treatment characteristics were also collected, entered multivariate analysis. Results eligible sample 196 patients. Spinal metastases distributed with approximately equal frequency (~27%) mobile semi-rigid segments. Rigid least spinal (19%). Patients metastatic regions experienced greater compared junctional subsections (Odds Ratio [OR] 1.37; p0.012). No relationship HR-QOL found. Multivariate analysis revealed that primary lung diagnosis reported worse those genitourinary cancers (OR 1.15; p0.05). Only age significantly (75–95yrs vs. 35–55yrs; p0.041). Conclusions an RT clinic have different distribution throughout surgery SBRT. Those segments more likely experience severe than Although further corroboration needed, our results suggest metastasis-bearing section could added existing list predictors aid clinicians identifying will benefit closer follow-up early intervention.