Anthracosis of the Lung: Evaluation of Potential Causes

作者: P Saeidi , M Mirsadraei

DOI:

关键词:

摘要: Anthracosis is black pigment discoloration of bronchi which can cause bronchial destruction and deformity (anthracofibrosis). A prospective, case-control study was performed to evaluate potential underlying causes anthracosis on 190 subjects who referred for various indications. Age patients ranged from 10-85 yrs. 46% male were farmers 27% manual workers, whereas 91% female housewives. During bronchoscopy, special attention given anthracotic plaque, deformity, infiltration, or vegetation. Broncho-alveolar lavage further cytopathological, acid-fast bacilli staining (AFB) culture in all cases. No correlation between occupational exposure dust two kinds (anthracotic plaque antracofibrosis) present. In anthracofibrotic patients, 81% nonsmokers. The principal finding bronchoscopy simple 21% anthracofibrosis 12%. Sputum smear showed macrophages containing granules 71%. Patients with had positive histopathology tuberculosis (21%) that not significantly different without anthracosis. Of 40 22 anthracofibrosis, only one respectively proven have bronchogenic carcinoma statistically more common than the control group. Other etiology should be investigated. Iran J Med Sci 2005; 30(4): 190-193.

参考文章(9)
J P Plisson, M A Billon-Galland, Ph Mulliez, E Dansin, X Janson, Anthracose bronchique et surcharge pulmonaire en micas Revue Des Maladies Respiratoires. ,vol. 20, pp. 267- 271 ,(2003)
Man Pyo Chung, Kyung Soo Lee, Joungho Han, Hojoong Kim, Chong H. Rhee, Yong Chol Han, O Jung Kwon, Bronchial Stenosis Due to Anthracofibrosis Chest. ,vol. 113, pp. 344- 350 ,(1998) , 10.1378/CHEST.113.2.344
F. Vanhoenacker, P. Van den Brande, A. De Schepper, Hepatosplenic antracosilicosis: a rare cause of splenic calcifications. European Radiology. ,vol. 11, pp. 1184- 1186 ,(2001) , 10.1007/S003300000717
Daye Wang, Yuko Minami, Yujian Shu, Sato Konno, Tatsuo Iijima, Yukio Morishita, Masayuki Noguchi, The implication of background anthracosis in the development and progression of pulmonary adenocarcinoma. Cancer Science. ,vol. 94, pp. 707- 711 ,(2003) , 10.1111/J.1349-7006.2003.TB01506.X
Atsunaka Kato, Jun Kagawa, Morphological effects in rat lungs exposed to urban roadside air. Inhalation Toxicology. ,vol. 15, pp. 799- 818 ,(2003) , 10.1080/08958370390217855
K Amoli, Bronchopulmonary disease in Iranian housewives chronically exposed to indoor smoke European Respiratory Journal. ,vol. 11, pp. 659- 663 ,(1998)
Mark J Roth, Wang Guo-Qing, Klaus J Lewin, Lu Ning, Sanford M Dawsey, Margaret N Wesley, Carol Giffen, Xie Yong-Qiang, Michelle M Maher, Philip R Taylor, Histopathologic changes seen in esophagectomy specimens from the high-risk region of Linxian, China: Potential clues to an etiologic exposure? Human Pathology. ,vol. 29, pp. 1294- 1298 ,(1998) , 10.1016/S0046-8177(98)90260-X
達生 飯嶋, 優子 南, 雅之 野口, 大業 王, The implication of background anthracosis in the develonment and progression of lung adenocarcinoma 肺癌. ,vol. 43, pp. 488- ,(2003)