Cross-correlation of virome-bacteriome-host-metabolome to study respiratory health.

作者: Lorenza Putignani , Bruno Dallapiccola , Andrea Onetti Muda , Simone Gardini , Andrea Iorio

DOI: 10.1016/J.TIM.2021.04.011

关键词:

摘要: A comprehensive understanding of the microbiome–host relationship in respiratory diseases can be elucidated by exploring landscape virome–bacteriome–host metabolome data through unsupervised 'multi-omics‘ approaches. Here, we describe how composition and function airway gut virome bacteriome may contribute to pathogen establishment propagation districts virome–bacteriome communities react diseases. new systems medicine approach, including characterization microbiome, crucial demonstrate likelihood odds disease pathophysiology, opening avenues discovery a chain causation for key bacteria viruses severity.

参考文章(108)
Efrem S Lim, Yanjiao Zhou, Guoyan Zhao, Irma K Bauer, Lindsay Droit, I Malick Ndao, Barbara B Warner, Phillip I Tarr, David Wang, Lori R Holtz, Early life dynamics of the human gut virome and bacterial microbiome in infants Nature Medicine. ,vol. 21, pp. 1228- 1234 ,(2015) , 10.1038/NM.3950
Jinfeng Wang, Yuan Gao, Fangqing Zhao, Phage-bacteria interaction network in human oral microbiome Environmental Microbiology. ,vol. 18, pp. 2143- 2158 ,(2016) , 10.1111/1462-2920.12923
Harald Martens, Quantitative big data: where chemometrics can contribute Journal of Chemometrics. ,vol. 29, pp. 563- 581 ,(2015) , 10.1002/CEM.2740
Nan Yan, Zhijian J Chen, Intrinsic antiviral immunity. Nature Immunology. ,vol. 13, pp. 214- 222 ,(2012) , 10.1038/NI.2229
Aleksandar D Kostic, Akinyemi I Ojesina, Chandra Sekhar Pedamallu, Joonil Jung, Roel G W Verhaak, Gad Getz, Matthew Meyerson, PathSeq: software to identify or discover microbes by deep sequencing of human tissue Nature Biotechnology. ,vol. 29, pp. 393- 396 ,(2011) , 10.1038/NBT.1868
Breck A Duerkop, Lora V Hooper, Resident viruses and their interactions with the immune system Nature Immunology. ,vol. 14, pp. 654- 659 ,(2013) , 10.1038/NI.2614
Herbert W. Virgin, The Virome in Mammalian Physiology and Disease Cell. ,vol. 157, pp. 142- 150 ,(2014) , 10.1016/J.CELL.2014.02.032
Poornima Ramanan, Jason N. Barreto, Douglas R. Osmon, Pritish K. Tosh, Rothia Bacteremia: a 10-Year Experience at Mayo Clinic, Rochester, Minnesota Journal of Clinical Microbiology. ,vol. 52, pp. 3184- 3189 ,(2014) , 10.1128/JCM.01270-14