Review of the Ultrastructure and Cytochemistry of Megakaryoblastic Leukemia

摘要: The term acute megakaryoblastic leukemia (AMKL) was introduced in 1931 [1]. However, a variety of names have been used to describe proliferations: myelosis, aleukemic myeloid megakaryocyte hepatosplenomegaly, malignant megakaryocytosis, with megakaryocytic predominance and micromegakaryoblastic leukemia. Thus it is difficult differentiate between the various reports. AMKL appears be rare disease. A survey literature discloses only few cases, FAB classification not mentioned [2]. controversy has prevented general acceptance this nosologic entity, because some cases also had many features myeloblastic Furthermore proliferation organ infiltration by precursors reported past wide range conditions, including chronic leukemia, thrombocythemia, myelosclerosis, erythroleukemia [3–61].