The ED95 of Nalbuphine in Outpatient‐Induced Abortion Compared to Equivalent Sufentanil

摘要: This prospective study evaluated the 95% effective dose (ED95 ) of nalbuphine in inhibiting body movement during outpatient-induced abortion and its clinical efficacy versus equivalent sufentanil. The was divided into two parts. For first part, voluntary first-trimester patients who needed induced abortions were recruited to measure ED95 using sequential method (the Dixon up-and-down method). In second this a double-blind, randomized study. Sixty cases randomly groups (n = 30), including group N (nalbuphine at dose) S (sufentanil an dose). Propofol given both as sedative. circulation, respiration surgery observed. amount propofol, awakening time, time leave hospital analgesic effect recorded. painless surgical 0.128 mg/kg (95% confidence intervals 0.098-0.483 mg/kg). Both sufentanil provided good intraoperative post-operative abortion. However, morbidity dizziness for less than (p < 0.05), significantly shorter those 0.05). Nalbuphine used showed better compared with