Epigenetics, Alcohol, and Cancer

摘要: Chronic or excessive alcohol consumption often leads to various medical disorders, including liver cirrhosis, pancreatitis, cardiomyopathy, fetal abnormalities, brain damage, and cancers. To effectively prevent treat these a better understanding of their underlying mechanisms is pivotal. Alcohol its metabolites alter cellular functions through changes at the levels DNA, RNA, protein, metabolites, resulting in pathophysiological changes. Although amount determined by dynamic processes synthesis degradation with many regulators involved, it initially predominantly activity genes involved. Two major gene regulation involve genetic epigenetic controls expression. In past half century, research technological innovations have led remarkable progress activities. However, only recent years, expression drew immense interest, especially biomedical fields cancer ageing. date, efforts understand effects on been primarily focused factors. The modifications alcohol-induced organ cancers, started be tackled few years.