Imidazol [1,2-a] pyridines and related compounds with activity at cannabinoid cb2 receptors

作者: Roger Olsson , Ethan Burstein , Anne Eeg Knapp , Jorgen Eskildsen , Joel Castillo

DOI:

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摘要: Disclosed are compounds of Formula (I) or (II) a pharmaceutically acceptable salt, ester, amide, prodrug thereof; and methods modulating the activity cannabinoid CB2 receptor comprising contacting compound with receptor. Said useful in treatment various condition disorders such as pain, neurodegenerative disorders.

参考文章(19)
Michael Milburn, Karl D. Normington, Chi B. Vu, Jean Bemis, Roger Xie, Joseph J. Nunes, Jill Milne, Fused Heterocyclic Compounds and Their Use as Sirtuin Modulators ,(2006)
Gregory E. Agoston, Lita Suwandi, Jamshed H. Shah, Theresa M. Lavallee, Anthony M. Treston, Todd A. Hembrough, Compositions and methods comprising proteinase activated receptor antagonists ,(2005)
Saskia Zemolka, Klaus Schiene, Thomas Tzschentke, Michael Haurand, Dagmar Kaulartz, Corinna Sundermann, Sven Kühnert, Stefan Oberbörsch, Thomas Christoph, Ruth Jostock, Substituted bicyclic imidazo-3-ylamine compounds ,(2005)
Janet Gunzner, Jonas Grina, Brad Newhouse, Steven Mark Wenglowsky, Joachim Rudolph, Kim Malesky, Wendy B. Young, Ellen R. Laird, Bainian Feng, Joshua D. Hansen, Li Ren, Simon Mathieu, Zhaoyang Wen, David Moreno, Kateri A. Ahrendt, Alexandre J. Buckmelter, Raf inhibitor compounds and methods of use thereof ,(2010)
Erica A. Kraynack, Alex Muci, Todd Tochimoto, Pu-Ping Lu, Bradley P. Morgan, David J. Morgans, Certain chemical entities, compositions and methods ,(2006)
Amanda L. Rousseau, Pulane Matlaba, Christopher J. Parkinson, Multicomponent synthesis of imidazo(1,2-a)pyridines using catalytic zinc chloride Tetrahedron Letters. ,vol. 48, pp. 4079- 4082 ,(2007) , 10.1016/J.TETLET.2007.04.008