Uncertainty of Prebiotic Scenarios: The Case of the Non-Enzymatic Reverse Tricarboxylic Acid Cycle
作者： Dmitry Yu Zubarev , Dmitrij Rappoport , Alán Aspuru-Guzik
DOI: 10.1038/SREP08009
关键词:
摘要: We consider the hypothesis of primordial nature non-enzymatic reverse tricarboxylic acid (rTCA) cycle and describe a modeling approach to quantify uncertainty this due combinatorial aspect constituent chemical transformations. Our results suggest that a) rTCA belongs degenerate optimum auto-catalytic cycles, b) set targets for investigations origin common metabolic core should be significantly extended.
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