1,25-Dihydroxycholecalciferol: Identification of the Proposed Active Form of Vitamin D3 in the Intestine
作者： A. W. Norman , J. F. Myrtle , R. J. Miogett , H. G. Nowicki , V. Williams
DOI: 10.1126/SCIENCE.173.3991.51
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摘要: The major polar metabolite of cholecalciferol (vitamin D3) present in chick intestinal mucosa has been chemically characterized by mass spectrometric analysis to have a molecular formula C27H4403 and structure 1,25-dihydroxycholecalciferol. This compound, which is produced the kidney from 25-hydroxycholecalciferol, previously shown be 4 13 times as active stimulating calcium transport. 1,25-Dihydroxycholecalciferol (previously designated 4B this (laboratory) probably represents biologically form intestine.
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