Regional ileitis (Crohn's disease). II. Electrolyte and water movement in the ileum during perfusion with bile acids.

摘要: Electrolyte and water movement was studied by steady state perfusion technique in the ileum of 11 patients with regional ileitis (Crohn's disease). Six who at time investigation had diarrhoea showed a constant secretion salts fluid during control perfusate. Per 24 hours, ileal effluents to colon would exceed normal amount 1-2 litres. In 5 without absorption patterns were normal. Electrolytes moved parallel. Dihydroxy bile acids enhanced or decreased respectively, two groups patients. It is concluded that functional disturbances salt inflamed may be significant physiological importance pathogenesis observed ileitis.