作者: Behzad Salari , Shabnam Samankan , Jahan Porhomayon
DOI: 10.1016/B978-0-12-800093-9.00002-8
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摘要: An increasing rate of type 2 diabetes (T2D) and obesity imposes a huge financial drain on healthcare systems. Diabesity describes their close pathophysiological clinical associations. Both are associated with an increased risk cardiovascular renal diseases. Multiple factors including biochemical, metabolic, genetic, cultural, psychosocial conditions contribute to insulin resistance. The coexistence T2D presents complex therapeutic management challenge remains undertreated in primary care. Lifestyle modifications remain the cornerstone such management. Medical treatment strategies for diabesity should be multifactorial, addressing its multiple metabolic abnormalities. Selection appropriate agents therefore becomes challenging, long-term monitoring is essential. There need newer anti-diabetic medications more effective weight-lowering properties. It hoped that scientific information derived from metabolite-profiling techniques will make it possible suggest individualized this chronic condition.