Acute colonic diverticulitis: modern understanding of pathomechanisms, risk factors, disease burden and severity

作者: Kjetil Søreide , Marja A. Boermeester , David J. Humes , George C. Velmahos

DOI: 10.1080/00365521.2016.1218536

关键词:

摘要: AbstractIntroduction: Conservative, non-antibiotic and non-surgical management of acute diverticulitis is currently being investigated. To better inform clinical decisions, understanding disease mechanisms, burden severity needed.Methods: Literature search risk factors, pathophysiology, epidemiology burden/severity reported over the last decade.Results: Acute a common has high burden. Incidence hospital admissions around 71 per 100,000 population, with increase in several subpopulations decades. The incidence likely to further aging populations. Risk factors for left-sided include dietary, anthropometric lifestyle factors. Disease mechanisms are still poorly understood, but distinction between inflammation infection emerging. integrative complex role gut microbiota become an interesting factor both ...

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