Implementation and characterization of an RF ion funnel ion guide as a proton transfer reaction chamber

摘要: Abstract A radio frequency ion funnel reaction chamber is applied for use with a proton transfer trap mass spectrometer (PIT-MS). The improvement in sensitivity over our dc-only drift tube ranged from 7.2 x isoprene to 65 x benzene. ideal settings of the are found be dc voltage 60 V, RF 240 V and pressure 1.80 mbar. An experimental theoretical investigation presented. Simulations using SIMION measurements m/z dependent transmission performed, as well simulations trajectories ions their survival probability. These used deduce greater understanding operation improvements. shown favor higher m/z, increase by combined effect focusing increased effective time. product an example set compounds measured systematically reagent branching profiles studied compared fragmentations. This represents important undertaking characterization studies technology PTR-MS.