Smartphones for cell and biomolecular detection.

作者: Xiyuan Liu , Tung-Yi Lin , Peter B. Lillehoj

DOI: 10.1007/S10439-014-1055-Z

关键词:

摘要: Recent advances in biomedical science and technology have played a significant role the development of new sensors assays for cell biomolecular detection. Generally, these efforts are aimed at reducing complexity costs associated with diagnostic testing so that it can be performed outside laboratory or hospital setting, requiring minimal equipment user involvement. In particular, point-of-care (POC) offers immense potential many important applications including medical diagnosis, environmental monitoring, food safety, biosecurity. When coupled smartphones, POC systems offer portability, ease use enhanced functionality while maintaining performance. This review article focuses on recent advancements developments smartphone-based within last 6 years an emphasis These devices typically comprise multiple components, such as detectors, sample processors, disposable chips, batteries, software, which integrated commercial smartphone. One most aspects developing is integration components onto compact lightweight platform requires power. Researchers demonstrated several promising approaches employing various detection schemes device configurations, expected further biosensors, battery miniaturized electronics will enable technologies to become more mainstream tools scientific communities.

参考文章(71)
M J Wolcott, Advances in nucleic acid-based detection methods. Clinical Microbiology Reviews. ,vol. 5, pp. 370- 386 ,(1992) , 10.1128/CMR.5.4.370
Isa Navruz, Ahmet F. Coskun, Justin Wong, Saqib Mohammad, Derek Tseng, Richie Nagi, Stephen Phillips, Aydogan Ozcan, Smart-phone based computational microscopy using multi-frame contact imaging on a fiber-optic array. Lab on a Chip. ,vol. 13, pp. 4015- 4023 ,(2013) , 10.1039/C3LC50589H
Jian Liu, Markus Enzelberger, Stephen Quake, None, A nanoliter rotary device for polymerase chain reaction. Electrophoresis. ,vol. 23, pp. 1531- 1536 ,(2002) , 10.1002/1522-2683(200205)23:10<1531::AID-ELPS1531>3.0.CO;2-D
Josep M. Llovet, Jordi Bruix, Molecular targeted therapies in hepatocellular carcinoma. Hepatology. ,vol. 48, pp. 1312- 1327 ,(2008) , 10.1002/HEP.22506
Christopher F. Fronczek, Tu San Park, Dustin K. Harshman, Ariana M. Nicolini, Jeong-Yeol Yoon, Paper microfluidic extraction and direct smartphone-based identification of pathogenic nucleic acids from field and clinical samples RSC Advances. ,vol. 4, pp. 11103- 11110 ,(2014) , 10.1039/C3RA47688J
Unyoung Kim, Sarah Ghanbari, Anusha Ravikumar, John Seubert, Silvia Figueira, Rapid, Affordable, and Point-of-Care Water Monitoring Via a Microfluidic DNA Sensor and a Mobile Interface for Global Health IEEE Journal of Translational Engineering in Health and Medicine. ,vol. 1, pp. 3700207- 3700207 ,(2013) , 10.1109/JTEHM.2013.2281819
Esko Strommer, Jouni Kaartinen, Juha Parkka, Arto Ylisaukko-oja, Ilkka Korhonen, Application of Near Field Communication for Health Monitoring in Daily Life international conference of the ieee engineering in medicine and biology society. ,vol. 2006, pp. 3246- 3249 ,(2006) , 10.1109/IEMBS.2006.260021
Barbara S Miranda, Elisângela M Linares, Stefan Thalhammer, Lauro T Kubota, None, Development of a disposable and highly sensitive paper-based immunosensor for early diagnosis of Asian soybean rust. Biosensors and Bioelectronics. ,vol. 45, pp. 123- 128 ,(2013) , 10.1016/J.BIOS.2013.01.048
Hongying Zhu, Sam Mavandadi, Ahmet F. Coskun, Oguzhan Yaglidere, Aydogan Ozcan, Optofluidic Fluorescent Imaging Cytometry on a Cell Phone Analytical Chemistry. ,vol. 83, pp. 6641- 6647 ,(2011) , 10.1021/AC201587A