Biology of Human Alkaline Phosphatases with Special to Cancer Reference

作者： William H. Fishman , Jose Luis Millan

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摘要: The current information on the cloning and sequencing of four alkaline phosphatase genes (PLAP, GCAP, LAP, TNAP) has been reviewed. It provided insights into their evolutionary history mechanisms catalysis uncompetitive inhibition. oncodevelopmental biology germ cell its excessive GCAP eutopic expression in neoplasia are noted, there is reason to suggest that enzyme may serve guide migratory cells transport specific molecules such as fat immunoglobulins across membranes. hyperexpression all observed various human tumors lines, particularly cancers testis ovary. membrane APs have investigated targets for immunolocalization immunotherapy.

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参考文章(207)

J Paiva, H Harris, P H Lange, I Damjanov, Immunohistochemical localization of placental-like alkaline phosphatase in testis and germ-cell tumors using monoclonal antibodies. American Journal of Pathology. ,vol. 111, pp. 156- 165 ,(1983)

O Lalos, Torgny Stigbrand, Ulf Stendahl, K Hirano, Katrine Riklund, B Tholander, Placental alkaline phosphatase (PLAP)/PLAP-like alkaline phosphatase as tumour marker in relation to CA 125 and TPA for ovarian epithelial tumours. European Journal of Gynaecological Oncology. ,vol. 11, pp. 351- 360 ,(1990)

Y Toh, Y Misumi, Y Ikehara, M Yamamoto, H Endo, Duplicate leader exons in the mouse liver-type alkaline phosphatase gene. Biochemistry international. ,vol. 22, pp. 213- 218 ,(1990)

Eric J. Stanbridge, Kathryn M. Latham, Examination of the oncogenic potential of a tumor-associated antigen, intestinal alkaline phosphatase, in HeLa x fibroblast cell hybrids. Cancer Research. ,vol. 52, pp. 616- 622 ,(1992)

T. Watanabe, N. Wada, E.E. Kim, H.W. Wyckoff, J.Y. Chou, Mutation of a single amino acid converts germ cell alkaline phosphatase to placental alkaline phosphatase. Journal of Biological Chemistry. ,vol. 266, pp. 21174- 21178 ,(1991) , 10.1016/S0021-9258(18)54836-5

M G Low, J B Finean, Release of alkaline phosphatase from membranes by a phosphatidylinositol-specific phospholipase C. Biochemical Journal. ,vol. 167, pp. 281- 284 ,(1977) , 10.1042/BJ1670281

M Bossi, M F Hoylaerts, J L Millán, Modifications in a flexible surface loop modulate the isozyme-specific properties of mammalian alkaline phosphatases. Journal of Biological Chemistry. ,vol. 268, pp. 25409- 25416 ,(1993) , 10.1016/S0021-9258(19)74407-X

I Vergote, M Onsrud, K Nustad, Placental alkaline phosphatase as a tumor marker in ovarian cancer. Obstetrics & Gynecology. ,vol. 69, pp. 228- 232 ,(1987) , 10.1016/0020-7292(87)90077-4

R Eliakim, K DeSchryver-Kecskemeti, L Nogee, W.F. Stenson, D.H. Alpers, Isolation and characterization of a small intestinal surfactant-like particle containing alkaline phosphatase and other digestive enzymes. Journal of Biological Chemistry. ,vol. 264, pp. 20614- 20619 ,(1989) , 10.1016/S0021-9258(19)47107-X

10.

J L Millán, Molecular cloning and sequence analysis of human placental alkaline phosphatase. Journal of Biological Chemistry. ,vol. 261, pp. 3112- 3115 ,(1986) , 10.1016/S0021-9258(17)35755-1

Biology of Human Alkaline Phosphatases with Special to Cancer Reference

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Biology of Human Alkaline Phosphatases with Special to Cancer Reference

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