The Immunologic and Immunochemical Basis for the Kiel Classification

摘要: As can be seen from the history of classification lymphomas (see p. 83ff.), morphologic analysis lymphoproliferative diseases did not advance beyond a certain state knowledge. The main reason is that characteristic features, such as organelles (granules, etc.), are found in most lymphoid cells. Since description and evaluation normal neoplastic cells highly subjective, very different concepts were developed, and, we now know, numerous misinterpretations appeared. For example, large lymphatic tissue usually mistaken for reticulum or “thrown into one pot” with real It known these represent definite functional forms cell series appear after antigenic stimulation. decades, morphologists also misinterpreted derivation plasma was said derived cells, 1 since it previously believed there transitional between them.