Rosette formation by peripheral lymphocytes.

摘要: In preparations of human peripheral lymphocytes suspended in serum absorbed with sheep red cells, up to 30% the may make rosettes erythrocytes. Washed Hanks' solution many if tested without delay. Such rapidly lose their capacity rosettes, but it can be restored by adding man or horse, rabbit guinea-pig. The three newborn babies, and one adult who had no detectable antisheep agglutinin serum, made cells. Rosette formation is uncorrelated levels. Many normal adults have far higher titres agglutinins against cells other animals than cells; yet do not these animals. Sodium cyanide (0·01 M) abolished rosette formation, horse antihuman lymphocyte globulin inhibits it. It concluded that cell due humoral antibody delayed hypersensitivity, because great proportion are capable it. Its nature obscure, suggested a substance, primarily an antibody, elaborated large circulating cross-reacts some antigens as plant lectins do. Caution advised using system test until more known about