Effects of Immunopotentiating and Immunomodulating Agents on Experimental and Clinical Herpesvirus Infections

摘要: As pointed out by Ching and Lopez (1979), patients with some types of immunodeficiency disorders, newborn infants, treated cytotoxic immunosuppressive drugs, either for cancer or organ transplantation, are prone to unusually severe infections herpesviruses (herpes simplex, cytomegalovirus, varicella-zoster). Herpes simplex virus (HSV) cytomegalovirus (CMV) a common cause morbidity mortality in bone marrow, renal, cardiac allograft recipients. A defect cell-mediated immunity CMV has been reported both children who excrete the first year life their mothers (Starr et al., 1979). It appears reasonable therefore assume that restoration immune capacity appropriate immunopotentiating agents might be way control severity herpesvirus immuno-deficient and, stretch imagination, such drugs even useful management immunologically normal subjects.