Challenges of Bone Metastases Treatment in Elderly Patients

摘要: Cancer rates are increasing, with the majority of cancer patients being over age 65. As global population ages and life expectancies increase, number elderly requiring treatment also increases, thus added challenges treating need to be addressed. This chapter outlines palliative radiotherapy for bone metastases. We will begin defining term elderly, outline recent demographic details cancer. An update on current status in clinical trials discussion factors that may affect enrolment these into given. With an emphasis trials, we discuss methods promote accrual this setting. A review safety efficacy is given, metastases determined advisable should recommended regardless age. Physical burden can alleviated by hypofractionated treatments, as multiple meta-analyses have demonstrated their equivalence pain control. In patients, more beneficial than other options, opioid-related adverse events greater population. Physicians continue encourage participation data forms basis guidelines. Radiation oncologists encouraged offer single treatments reduce physical treatments.