Ultrastructural evidence for CSF production by a choroid plexus papilloma

摘要: A choroid plexus papilloma (CPP) removed from a child with communicating hydrocephalus was studied the electron microscope. In addition to usual organelles, neoplastic epithelial cells contained polypoid microvilli, cilia, coated pinocytotic vesicles, and apical tight junctions. The basal surfaces were consistently juxtaposed large capillaries lined by fenestrated endothelium. fine structural details of tumor essentially same as those normal CP thus appeared ideally suited for an active secretory function. Two additional features in this tubular bodies endothelium well developed pericytes. present findings provide strong evidence cerebrospinal fluid production CPP, phenomenon that has long been suggested clinical observation.