The NFκB Expression on Apical Dental Granuloma: An Immunohistochemistry Analysis.

作者: Risya Cilmiaty , Nirawati Pribadi , Mandojo Rukmo , Meircurius Dwi Condro Surboyo

DOI: 10.2147/CCIDE.S256284

关键词:

摘要: Background Endodontic treatment on dental caries with granuloma the periapical has potential to flare. The symptoms of acute flare in are strongly related activation macrophages that produce pro-inflammatory cytokine through nuclear factor kappa B (NFκB). However, role NFκB not been widely explained. Purpose To compare expression and nongranuloma caries. Methods lesion was obtained from patients who were subjected tooth extraction. confirmed by radiography then differentiated histological immunohistochemistry analyzing expression. Results Most granulomas found females (66.67%) between ages 36 45 (61.11%). Dental showed higher compared lesions (p=0.021). Conclusion tissue an increase Understanding might provide additional insights into process development.

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